Cynthia Crawford

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Cynthia Crawford
Director of Research and Grants
Professor of Psychology

Phone: (909) 537-7415
Office: SB-524

Ph.D. in Behavioral and Neural Studies, University of Kentucky, 1996.
M.A. in Behavioral and Neural Studies, University of Kentucky, 1989.
B.A. in Psychology, Washington University, St. Louis, 1985.

Dr. Crawford's area of specialization includes animal models of drug addiction, second messenger system pharmacology, and developmental neuropsychopharmacology. Dr. Crawford first became interested in psychological research after watching her grandfather endure the motor and cognitive decay of Parkinson's disease. She was amazed at how much doctors and researchers simply did not know about brain-related disorders, but knew that the answers were to be found in research. Dr. Crawford's initial interest in learning and memory eventually evolved into an interest in neuroscience after observing the existence of many individual differences in drug effects across the lifespan. She became interested in psychopharmacology and using drugs as a tool to figure out how the brain works by understanding the interaction between drugs and the brain. Dr. Crawford is most interested in the effects of psychostimulants among different age groups.

Selected Publications:

Crawford, C.A., Villafranca, S.W., Cyr, M.C., Farley, C.M., Reichel, C.M, Gheorghe, S.L., Krall, C.M., McDougall, S.A. Effects of early methylphenidate exposure on morphine-and sucrose-reinforced behaviors in adult rats: Relationship to dopamine D2 receptors. Brain Research, under revision.

Farley, C.M, Baella, S.A., Wacan, J.J, Crawford, C.A., McDogouall, S.A. (2006). Pre- and postsynaptic actions of a partial D2 receptor agonist in reserpinized young rats: Longevity of agonistic effects. Brain Research, 1124, 37-44.

Reichel, C.M., Wacan, J.J., Farley, C.M., Stanley, B.J., Crawford, C.A., McDougall, S.A. (2006). Postnatal manganese exposure attenuates cocaine-induced locomotor activity and reduces dopamine transporters in adult male rats. Neurotoxicology and Teratology, 28, 323-332.

Crawford, C.A, William, M.T., Kohutek, J.L., Choi, F.Y., Yoshida, S. T., McDougall, S.A., Vorhees, C.V. (2006). Neonatal 3,4-methylenedioxymethamphetamine (MDMA) exposure alters neuronal protein kinase A activity, serotonin and dopamine content, and [35S]GTP?S binding in adult rats, Brain Research, 1077, 178-186.

Yoshida, S.T., Baella, S.A., Stuebner, N.M., Crawford, C.A., McDougall, S.A. (2006). Effects of a partial D2-like receptor agonist on striatal dopamine autoreceptor functioning in preweanling rats, Brain Research, 1073-1074, 269-275.

Lit, L. Crawford C.A. (2006). Effects of training paradigms on search dog performance. Applied Animal Behaviour Science, 98, 277-292.

McDougall, S, A., Reichel, C.M., Cyr, M.C., Karper, P.E., Nazarian, A., Crawford, C.A. (2005). Importance of D1 receptors for associative components of amphetamine-induced behavioral sensitization and conditioned activity: A study using D1 receptor knockout mice. Psychopharmacology, 183, 20-30.

Armstrong, V., Reichel, C.M., Doti, J.F., Crawford, C.A., McDougall, S.A. (2004). Repeated amphetamine treatment causes a persistent elevation of glial fibrillary acidic protein in the caudate-putamen. European Journal of Pharmacology, 488, 111-115.

Crawford, C.A., Choi, F.A., Kohutek, J, Yoshida, S.T., and McDougall, S.A. (2004). Changes in PKA activity and Gsa and Golfa levels after amphetamine- and cocaine-induced behavioral sensitization. Synapse, 51, 241-248.

Crawford, C.A., Willimans, M.T., Newman, E.R., McDougall, S.A., and Vorhees, C.V. (2003). Methamphetamine exposure during the preweanling period causes prolonged changes in dorsal striatal protein kinase A activity, dopamine D2-like binding sites, and dopamine content. Synapse, 48, 131-7.